A human prostatic bacterial isolate alters the prostatic microenvironment and accelerates prostate cancer progression
نویسندگان
چکیده
منابع مشابه
Benign prostatic hyperplasia and prostate cancer.
Benign prostatic hyperplasia refers to an anatomic diagnosis, yet in practice it is typically diagnosed clinically on the basis of lower urinary tract symptoms and prostatic enlargement detected on manual rectal examination or transrectal ultrasonography (1). Over the past decade, since benign prostatic hyperplasia (2) and prostate cancer (3) were reviewed in this Journal, there has been a prol...
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Background: Different studies assessed the role of inflammation in malignancy of different organs. Prostatitis has been suggested as a cause of cancer and BPH. Till now, more than 100 types of human Papilloma virus (HPV) are recognized including low and high-risk groups for carcinogenesis. Among them HPV-16 and HPV-18 have shown further association with cancer. Regarding the pr...
متن کاملThe impact of benign prostatic hyperplasia on bladder volume in radiotherapy of prostate cancer
Background: Benign prostatic hyperplasia (BPH) is a common disease among older men and many patients with prostate cancer (PC) also have BPH. External beam radiation therapy (EBRT) is one of the important treatments for PC, nevertheless, few studies have analyzed the effect of BPH on EBRT. We tried to know the risk of bladder toxicity by analyzing the bladder volume variability in patients with...
متن کاملWhile Urine and Plasma Decorin Remain Unchanged in Prostate Cancer, Prostatic Tissue Decorin Has a Prognostic Value
Background: Numerous studies confirmed that significant decrease in tissue decorin (DCN) expression is associated to tumor progression and metastasis in certain types of cancer including prostate cancer (PC). However, the potential prognostic value of tissue DCN in PC has not yet been investigated. Methods: A total number of 40 PC and 42 patients with benign prostatic hyperplasia (BPH) were inv...
متن کاملProstatic specific antigen for prostate cancer detection.
Prostate-specific antigen (PSA) has been used for prostate cancer detection since 1994. PSA testing has revolutionized our ability to diagnose, treat, and follow-up patients. In the last two decades, PSA screening has led to a substantial increase in the incidence of prostate cancer (PC). This increased detection caused the incidence of advanced-stage disease to decrease at a dramatic rate, and...
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ژورنال
عنوان ژورنال: The Journal of Pathology
سال: 2015
ISSN: 0022-3417
DOI: 10.1002/path.4472